Home - Illumos | Next Generation Pathology

What 3D features do you want to see?

Because it is finally possible

3D Pathology for everyone

Biology should be 3D and accessible

Thy1-GFP Mouse Brain Dentate gyrus 3D IHC

Ground-truth data at 1,000x throughput

The foundation for accurate diagnosis

About Us

We are a Hong Kong-based startup who are unsatisfied with current tissue diagnostics.

We challenge ourselves to develop pragmatic new technologies to surpass existing diagnostics limits and improve patient outcomes.

Our Mission

We develop 3D tissue diagnostics to assess the breadths and depths of tissue samples from biopsies and surgeries. The data is quantitative and accurate, allowing us to find the best drug options for the patients.

In contrast, current tissue diagnostics is limited to 2D, a flat and limited view causing inaccurate quantification and missed features. >50% cancer therapy fails if there is no accurate test to guide treatment, which is worse than a coin flip.

Our Tech

Developing 3D diagnostics is not trivial, requiring precise control of protein and light movements across tissue samples without damage and the analysis of massive image datasets.

Our platform quantifies multiple protein biomarkers across millions of cells in intact 3D tissue, preserving spatial relationships. This is achieved through advanced chemical staining, tissue clearing, and imaging with custom laser microscopes.

Latest Milestone

To date, we can reliably analyze 2mm thick tissue in 3D H&E staining in 5 minutes and 5mm tissue blocks within 24 hours. Immunostaining with 4 biomarkers per round can be achieved in a day per millimeter of tissue. Our platform is compatible with fixed and wax-embedded specimens, and the process requires no specialized equipment and preserves tissue at the molecular level.

Partner with us to advance cancer diagnosis and treatment.

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